Pharmaceutical Intermediates
| for API | Intermediates | CAS No. |
| Aceclofenac | Aceclofenac Tert-Butyl Ester | 139272-68-7 |
| Adapalene | Methyl 6-bromo-2-naphthoate | 33626-98-1 |
| 1-(5-bromo-2-methoxy-phenyl)adamantane;1-(5-bromo-2- methoxyphenyl)-tricyclo(3.3.1.13,7)decane; 2-(1-adamantyl)-4-bromo-anisole |
104224-63-7 | |
| Aprepitant | 2-(2-Chloro-1-iminoethyl)hydrazinecarboxylic acid methyl | 155742-64-6 |
| (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine HCl | 171482-05-6 | |
| Arbidol hcl | Arbidol Base | 131707-25-0 |
| Aripiprazole | 1-(2,3-Dichlorophenyl) piperazine HCl | 119532-26-2 |
| 7-(4’-Bromobuthoxy)-3,4-dihydro-2(1H) Quinolinone | 129722-34-5 | |
| 7-Hydro-3,4-dihyro-2(1H)-quinoline | 22246-18-0 | |
| Atorvastatin | (4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-3-phenyl- 4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-dioxane-4-acetate(L-1) | 125971-95-1 |
| Azathioprine | 6-Mercaptopurine, | 50-44-2 |
| 5-Chloro-1-methyl-4-nitroimidazole | 4897-25-0 | |
| Azithromycin | Azithromycin Amine | 76801-85-9 |
| Bosentan | 2-Pyrimidinecarboximidamide hydrochloride | 138588-40-6 |
| 5-(2-methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1h,5h)-dione | 150728-12-4 | |
| 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-Bipyrimidine | 150728-13-5 | |
| Capecitabine | 2,3-Dioacetyl-5’-deoxy-5-fluorocytidine | 161599-46-8 |
| 1,2,3-Triacetoxy-5-Deoxy-D-Ribose | 62211-93-2 | |
| Cinacalcet | (S)-Alpha,Alphal-Diphenyl-3-Pyrrolidineacetamide-L-tartrate | 134002-26-9 |
| 3-[3-(Trifluoromethyl)Phenyl]Propionaldehyde | 21172-41-8 | |
| Ciprofloxacin | Ciprofloxacin Acid | 86393-33-1 |
| Clavulanate Potassium |
Tert-butylamine Clavulanate,(TBA) | |
| Clopidogrel | Methyl 2-(2-chlorophenyl)-2-((2-(thiophen-2-yl)ethyl)aMino)acetate hydrochloride | 141109-18-4 |
| Cobicistat | 2-isopropylthiazol-4-yl)-N-methylmethanamine | 154212-60-9 |
| 2-isopropylthiazol-4-yl)-N-methylmethanamine 2HCL | 1185167-55-8 | |
| Darunavir | 4-Amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenyl butyl]-N-isobutylbenzenesulfonamide(D7) | 169280-56-2 |
| (3aS,4S,6aR)-4-methoxytetrahydrofuro[3,4-b]furan-2(3H)- | 866594-60-7 | |
| (3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-ß]furanyl Succinimidyl Carbonate(SM9) |
253265-97-3 | |
| Diclofenac Sodium |
N-(2,6-DICHLOROPHENYL)-2- INDOLINONE | 15362-40-0 |
| Dolutegravir | （R）-3-amino-1-butanol | 61477-40-5 |
| 2H-Pyrido[1',2';4,5]pyrazino[2,1-b][1,3]oxazine-6,8- dione,3,4,12,12a-tetrahydro-7-(phenylmethoxy) |
1299006-34-1 | |
| 2H-Pyrido[1',2';4,5]pyrazino[2,1-b][1,3]oxazine-6,8-dione,9- bromo-3,4,12,12a-tetrahydro-7-(phenylmethoxy) |
1229006-35-2 | |
| 1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5- pyridinedicarboxylic acid 2-methyl ester |
1335210-23-5 | |
| (4R,12aS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8- dioxo-3,4,6,8,12,12a-hexahydro-2H-[1 ,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9carboxamide |
1335210-35-9 | |
| Efavirenz | 4-Chloro-2-(Trifluoroacetyl)aniline Hydrochloride | 173676-59-0 |
| (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3- cyclopropyl-2-propyn-1-ol(E05) |
209414-27-7 | |
| Empagliflozin | (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4- [[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D- |
915095-99-7 |
| emtricitabine | (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME) | 147126-75-8 |
| Entecavir | (1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane | 110567-22-1 |
| 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3- (benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one |
142217-81-0 | |
| 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine | 204845-95-4 | |
| Etoricoxib | 4-Methylthio Benzaldehyde | 3446-89-7 |
| Etravirinem | Dimethyl-4-hydroxybenzonitrile | 4198-90-7 |
| Febuxostat | ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate | 161797-99-5 |
| ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5- | 161797-99-5 | |
| Gliclazide | N-Amino-3-Azabicyclo[3,3,0]-Octan Hcl | 58108-05-7 |
| Methylphenylsulfonylurea | 1694-06-0 | |
| Ibrutinib | 4-Phenoxybenzoic acid | 2215-77-2 |
| 2-[(Methoxy)(4-phenoxyphenyl)methylene]malononitrile | 330792-69-3 | |
| (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4- d]pyrimidin-4-amine |
1022150-12-4 | |
| Indapamide | 1-amine-2-Methylindolin Hcl | 31529-47-2 |
| 4-Chloro-3-Sulfomul benzoic Acid | 1205-30-7 | |
| Ivabradine | 7，8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one | 20925-64-8 |
| 7，8-dimethoxy-1,3-dihydro-2H-benzazepin-2-one | 73942-87-7 | |
| 3-(3-chloropropyl)-7,8-dimethoxy-1,3-dihydro-2H-3- benzazepin-2-one |
85175-59-3 | |
| 3-(3-chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3- Benzazepin-2-one, |
85175-65-1 | |
| (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane hydrochloride | 866783-13-3 | |
| Letermovir | 1-(3-Methoxyphenyl)piperazine | 16015-71-7 |
| 1-(3-Methoxyphenyl)piperazine dihydrochloride | 6968-76-9 | |
| Metoprolol | 4-(2-Methoxyethyl)-phenol | 56718-71-9 |
| Montelukast | Methyl [E]-2-[3-(S)-[3-[2-(7-Chloro-2- quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoate |
142569-69-5 |
| 181139-72-0 | ||
| 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3- hydroxypropyl)phenyl)-2-propanol |
142569-70-8 | |
| 2-[1-(Mercaptomethyl)cyclopropyl]acetic acid | 162515-68-6 | |
| Nevirapine | 2-Chloro-3-amino-4-methyl pyridine | 133627-45-9 |
| 2-Chloro-N-(2-chloro-4-methyl-pyridin-3-yl)nicotinamide | 133627-46-0 | |
| 3,5-Dimethyl-4-hydroxy benzonitrile | 4198-90-7 | |
| Osimertinib | 3-(2-chloropyrimidin-4-yl)-1-methylindole | 1032452-86-0 |
| 4-fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | |
| N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3- yl)pyrimidin-2-amine |
1421372-94-2 | |
| Palbociclib | 5-Bromo-2-nitropyridine | 39856-50-3 |
| 4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl | 571189-16-7 | |
| tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | |
| Paroxetine | (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1- | 105812-81-5 |
| (3S)-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine | 109887-53-8 | |
| Pazopanib | 2,4-Dichloropyrimidine(pazopanib int) | 3934-20-1 |
| 5-Amino-2-methylbenzenesulfonamide(pazopanib int) | 6973-09-7 | |
| 2,3-dimethylindazol-6-amine hydrochloride(pazopanib int) | 635702-60-2 | |
| Perindopril | L-Norvaline | 6600-40-4 |
| (S)-(-)-Indoline-2-carboxylic acid | 79815-20-6 | |
| L-Octahydroindole-2-carboxylic acid | 80875-98-5 | |
| (2s,3as,7as)-octahydro-1h-indole-2-carboxylic acid | 80875-98-5 | |
| N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine | 82834-12-6 | |
| Posaconazole | (5R-cis)-Toluene-4-sulfonicacid5-(2,4-difluorophenyl)-5-(1H- 1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester |
149809-43-8 |
| 2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4- hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one |
184177-83-1 | |
| Prasugrel | Cyclopropane carboxylic acid | 1759-53-1 |
| Cyclopropyl 2-fluorobenzyl ketone | 150322-73-9 | |
| 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-Ethanone | 204205-33-4 | |
| 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one | 115473-15-9 | |
| 4,5,6,7-Tetrahydrothieno[2,3-c]pyridine-2-onium PTSA | 952340-39-5 | |
| Pregabalin | (±)-3-(Carbamoymethyl)-5-methylhexanoic acid | 181289-15-6 |
| Rasagiline Mesylate |
( R)-(-)-1-aminoindan hydrochloride | 10305-73-4 |
| 1-aminoindan hydrochloride | 70146-15-5 | |
| Raltegravir | 4-amino-n-[(2r,3s)-3-amino-2-hydroxy-4-phenylbutyl]-n- isobutylbenzene-1-sulfonamide （Raltegravir int） |
518048-03-8 |
| 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt （Raltegravir int） |
888504-28-7 | |
| Rivaroxaban | (s)-(+)-glycidyl phthalimide | 161596-47-0 |
| 1H-isoindole-1,3(2h)-dione,2-[[(5s)-2-oxo-3-[4-(3-oxo-4- morpholinyl)phenyl]-5-oxazolidinyl]methyl] |
446292-08-6 | |
| Ropivacaine | N-(2,6-Dimethylpheny1)-2-piperidineCarboxamide | 15883-20-2 |
| Rosuvastatin | N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide;4-(4- Fluorophenyl)-6-lsopropyl-2-(N-Methyl-N- | 147118-36-3 |
| N-[4-(4-fluorophenyl)-5-formyl-6-(propan-2-yl)pyrimidin-2-yl]- N-methylmethanesulfonamide,4-(4-Fluorophenyl)-6- Isopropyl-2-(N-Methyl-NMethylsulphonylamino)-5-Pryimidine Carboxaldehyde(Z8.1 or Z-8) | 147118-37-4 118442-83-4 |
|
| (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2- [methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2- dimethyl-1,3-dioxane-4-acetic Acid1,1-Dimethylethyl Ester,Rosuvastatin calcium intermediate R-2(R-1) | 289042-12-2 | |
| (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6- heptane acid,dimethylethyl ester;Rosuvastatin calcium intermediate R-3;(Rosuvastatin tert-Butyl Ester) | 355806-00-7 | |
| Simvastatin | Simvastatin Ammonium salt (N-1) | 139893-43-9 |
| Sitagliptin | Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid | 486460-00-8 |
| 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3- | 486460-21-3 | |
| Methyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate | 769195-26-8 | |
| Sofalcone | 1-Bromo-3-Methyl-2-Buten | 870-63-3 |
| Solifenacin Succinate | (R)-(-)-3-Quinuclidinol | 25333-42-0 |
| (R)-(-)-3-Quinuclidinol HCl | 42437-96-7 | |
| 1-phenyl-1,2,3,4-tetrahydro-isoquinoline | 22990-19-8 | |
| (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline | 118864-75-8 | |
| Tagrisso | 3-(2-Chloropyrimidin-4-yl)-1-methylindole | 1032452-86-0 |
| 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | |
| N,N,N’-Trimethylethylenediamin | 142-25-6 | |
| Talgrefovir | 2-(2-AMinopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1- Methyl-6-oxo-1,6-dihydropyriMidine-4-carboxaMide |
518048-03-8 |
| Tenofovir | (R)-(+)-9-(2-Hydroxypropyl)adenine | 14047-28-0 |
| Diethyl (tosyloxy)methylphosphonate | 31618-90-3 | |
| 6-Amino-purine | 73-24-5 | |
| Voriconazole | (2R,3S/2S,3R)-3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4- difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol Hcl |
188416-35-5 |
| (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4- pyriMidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol |
188416-29-7 | |
| Zofenopril Calcium |
3-(Benzoylthio)-2-methylpropanoic acid | 74431-50-8 |
| (S)-(-)-3-Benzoylthio-2-methylpropanoic acid | 72679-02-8 |
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